Origin: MO | Grant Awarded: Replant | Status: Acquired

Visit Website →

What is CareSignal?

CareSignal is the developer of a remote patient monitering platform that creates and validates disease-specific  digital inerventions to help care teams manage and support medically underserved patient populations. 

Company Leadership

blake marggraff


Blake leads CareSignal in developing evidence-based healthcare technology to deliver clinical and financial returns for patients and healthcare organizations who have the most to gain. CareSignal, founded in 2015, serves dozens of large health systems and payers across the United States. The company’s technology has been recognized by the 2018 Forbes Impact Summit and Prime Healthcare Competition, and its clinical impact is evidenced by ten positive-outcome peer reviewed journal publications. Blake has experience as in hard sciences research, and previously co-founded and grew the education technology startup BetaBox Labs to cashflow positive. Blake’s vision is to create a new standard of care for United States patients across the most prevalent chronic conditions.

Blake grew up in the Bay Area of California. An Eagle Scout, his favorite merit badges were nuclear science and entrepreneurship. What began as a home-brew x-ray machine in the back of a public high school classroom led Blake to win the Intel Science and Engineering Fair in 2011 by using tin microparticles to improve cancer treatment, for which he was named top Teenage Inventor by Popular Science. Blake attended Washington University’s undergraduate Biology program, graduating in 2015. Blake serves on the board of the healthcare access nonprofit iFM Family Medicine, mentors promising student-entrepreneurs at each year at the University of Missouri, St. Louis, and enjoys backpacking and rock climbing.

Connect on LinkedIn →

Involved Industries

Be a Part of the Movement

We champion extraordinary entrepreneurs to create positive change – for St. Louis and for the world. Join us by applying to our Global Startup Competition, becoming a financial supporter, volunteering your time or amplifying our message.